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Monday, October 26, 2015

College of Idaho - LAB STUDIES VAPE EFFECTS ON BONE HEALTH

Enjoy the puff, without the harmful stuff. That’s how electronic cigarettes have been marketed. But with little research on how e-cigarettes and vaping can affect the human body, questions remain as to how safe this rapidly growing “safer alternative” to smoking really is.

After hearing that traces of heavy metals have been found in the vapor of e-cigarettes, College of Idaho biology professor Dr. Sara Heggland and her INBRE (IDeA Network of Biomedical Research Excellence) lab decided to investigate.

“There are no federal regulations on what they put in the e-liquids,” Heggland said. “So it is kind of an open-ended, ‘what is this doing to the body?’ ”

And more specifically, Heggland and C of I junior Maggie Brown wanted to see how e-liquids affect bone health. So, they chose three different flavors of e-liquids (Mango Blast, Irish Latte and Sweet Melon), with and without nicotine, to expose bone cells to and test their ability to live. Heggland and Brown also wanted a non-flavored e-liquid to serve as the control. That didn’t exist in local vape shops, so Heggland had it custom made.

Part of the difficulty in performing the tests was deciding which e-liquids to test because there are so many flavors and varieties. And the fact that there is no standardization among e-liquids, and the liquid can vary from brand to brand and even from bottle to bottle, added to that difficulty.

The research team also wanted to figure out a way to vape the e-liquid and collect the vapor in a liquid extract to treat the cells. So they designed their very own vaping contraption in the lab with the help of C of I biology professor Dr. Luke Daniels. And early results showed an interesting pattern.
“We saw the flavored liquids had a more pronounced decrease in cell viability than our non-flavored e-liquids,” Brown said about the preliminary results. “But this is consistent with the findings of other researchers.”

Extravagant flavors are one of the biggest differences between tobacco cigarettes and their electronic cousins. Tobacco cigarettes cannot be flavored with anything other than menthol, because flavoring has proven to be an effective marketing strategy to target younger users. On the other hand, the flavors for e-cigarettes range from cotton candy and bubble gum to sweet melon and strawberrylicious. A 2012 report from the Centers for Disease Control estimated that 1.78 million students in grades 6-12 had tried e-cigarettes, though some states have legislation preventing the sale of e-cigarettes to minors.

While conducting the tests, Heggland and Brown weren’t sure if directly exposing bone cells to e-liquids would be of any relevance. But after hearing that young children have been able to open the bottles and drink them, resulting in nicotine poisoning, another dimension has been added to their research, Heggland said.

And after observing that e-liquids do decrease a cell’s ability to live, the next question for the lab is, “what is causing this decrease in cell viability?” That’s a question Heggland and Brown will continue to pursue as the school year goes on.

“I’m really excited,” Brown said. “There are a lot of different avenues we can go down. Since the research [on e-cigs] is so limited, there is a lot that we can figure out.”

For Brown, the chance to get hands-on experience as an undergraduate was a major checklist item she had as she applied to colleges in pursuit of her larger dream to go to medical school.
“I found participating in INBRE and participating in the lab during the school year has been an amazing opportunity,” said Brown, who started out in Heggland’s lab by learning cell culture techniques.

And while Heggland is excited about the addition of this new project to her lab, she’s also enjoyed seeing Brown’s enthusiasm. After all, seeing a student eagerly pursue their research is the biggest reward of teaching, she said.

“My research lab is my classroom,” Heggland said. “I love getting students in the lab, getting them excited about science, taking ownership of a project and helping them through the ups and downs.”

(Click Here) to view original article.
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How to Talk to Your Teen About Vaping

It's a new generation, and there's another way to hook kids on nicotine. In a few short years, e-cigarettes and other vaping devices have shot up in popularity. They're the latest method to deliver nicotine ­along with mixtures of chemicals that users suck into their lungs.

For kids, vaping may seem like a fun, harmless, social experience. But for parents, vaping is both an X-factor and an all-too-familiar echo of the past. Toxins masked with sweet candy flavors and marketed as cool social props feels similar to the way tobacco cigarettes were sold for decades.

Below, two doctors (parents themselves) who've blogged about teens and vaping suggest how to open a conversation with your kids.

Old Tactics/New Devices

For a look at how the cigarette industry targeted young people, browse the Truth Tobacco Industry Documents, a now-public collection of studies, reports and memos created by tobacco companies. Documents include insider information on tactics for attracting new, youthful customers. (Remember candy-flavored cigarettes and Joe Camel?)

Today, vaping products are available in fruit, candy and dessert flavors. By clicking an online button assuring they're over 18, kids can order strawberry, peach, blueberry and coconut blends; doughnut and "Belgian waffle" flavors; and chocolate, cherry and cotton candy choices among countless others.

Dr. Pia Fenimore, a pediatrician with Lancaster Pediatric Associates in Pennsylvania, first heard of vaping from a teen patient with whom she'd previously worked to help quit smoking. "She was the one that said to me, 'It's not tobacco. It's safe, and it's a way for me to not miss my cigarettes. And it even smells good,'" Fenimore says. "She showed it to me, and it smelled just like a lollipop. And I thought, 'Oh, no.'"

An in-depth article by Janet Raloff, published June 30 in ScienceNews, digs into the dangers e-cigarettes hold for teens. Developing young brains may be more vulnerable to nicotine's effects. It is possible to vape without nicotine; non-nicotine products are available. But that doesn't mean all the risk is removed. Chemicals may damage lung tissue and disrupt the barrier function of the lungs.
Vaping has alternate uses. In a confidential survey of Connecticut high school students who use e-cigarettes, 18 percent reported vaping marijuana at some point.

Talking With Teens

"There's a lot of good news about cigarette smoking dropping off­­ – kids have definitely gotten the message that smoking is bad," says Dr. Laura Offutt, founder of the teen health website Real Talk With Dr. Offutt. Unfortunately, she says, kids are now getting a marketing message that vaping is an acceptable replacement.

It's harder to detect if kids are using e-cigarettes than traditional smoking, Offutt says. "They won't have smoke on their breath," she says. "But they might have bloodshot eyes. Or they may show signs of nicotine withdrawal," she adds, like the irritability adult cigarette smokers can experience. She's posted sample pictures of vaping devices on her website. "So if parents see anything that looks like that and they're not sure what it is, that could be a clue," she says. 

When talking to your teens about vaping, play it casual, Offutt recommends. "It's not really a judgmental way to ask the question," she says. "It's more just, 'I've read this, and I'm curious what you've heard about it.' Or, 'Do you know any kids that are using e-cigarettes?' or 'What do your classmates think about e-cigarettes?' It's a nice way to open that conversation."

Keep it open-ended, Fenimore agrees: "You don't want to ask a yes-no question. Because teenagers will look for any chance to answer a question with a yes or no. Then you're really nowhere."

Today's teens are more health-savvy, Fenimore says. "When you tell them nicotine can lead to high blood pressure, fatigue and sudden mood changes, and that it can lead to a lifelong, expensive and health-harming addiction, those [are] things they want to avoid for themselves."

Stress the seriousness of vaping, Fenimore says, as a decision to not just make on a whim, but one with potential consequences of lifelong problems. "It's not like drinking a slushy or some other thing you like just because of the flavor," she says. "This is really a serious drug."


Finally, be the message. If you don't want your kids to vape, don't vape, either. "Children of people that use products like vaping and nicotine products are more likely to use them," Fenimore says. "They are less likely to listen to people like me and their teachers if their parents are sending – whether they mean to or not – that subliminal message of, 'Oh well, it's actually OK.'"

(Click Here) to view original article
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Monday, September 21, 2015

The vape debate: Is it good or bad for Orange County to be the 'Silicon Valley' of vaping?

BY LAUREN A. WILLIAMS / STAFF WRITER
Vaping laws around Orange County:
-Buena Park, Garden Grove and Laguna Niguel have passed laws banning vaping in public places where California law bans tobacco smoking. Laguna Niguel also prohibits e-cigarette lounges because they are not listed in the city's zoning code.
-Mission Viejo and Seal Beach have interpreted existing city laws banning tobacco smoking in parks to include e-cigarettes.
-Costa Mesa is banning vaping in public facilities and parks.
-San Clemente officials considered a ban on vaping in public places but decided to wait to learn more about whether secondhand vapor is as dangerous as secondhand smoke.
-The OC Fair prohibits e-cigarettes in the amphitheater, grandstand and bleacher seating areas.
Sources: City staff, municipal code and American Nonsmokers' Rights Foundation
– Jordan Graham


Randy Freer is all in on the vaping business, even if he worries that pending laws and regulations could make him go bust.

Freer’s construction career dried up during the housing crisis, and he became an entrepreneur. In spring 2013 he launched P.O.E.T., a boutique Seal Beach-based manufacturer of e-liquid, or “juice” as it’s called – the stuff loaded into vaping devices to create an inhalable vapor that simulates cigarette smoke.

Freer sees himself as an artisan. Creating new flavors of vaping liquid, “electronic nectar” as he calls it, is akin to crafting a high-end alcoholic beverage layered with differ-ent tastes. “It’s almost like a fine whiskey or a fine wine,” he said. “You can start to pick the layers apart in the flavor profile.”

Freer is far from alone in his enthusiasm. As vaping has caught on, it has attracted legions of aficionados here – not only the ones who inhale the stuff but also entrepreneurs staking their claim to a burgeoning industry. Orange County has become a vaping hub – home to 15 percent to 20 percent of e-liquid manufacturers in the U.S., by one estimate.
Health concerns

Not everyone, however, is as enamored of vaping as are Freer and his peers in the business. The growing distribution of an essentially unregulated product has drawn the attention of lawmakers, regulatory agencies, city officials and the medical establishment.
And their scrutiny has intensified with the appearance of studies showing that the chemicals contained in the liquid inhaled by vapers may have serious health consequences.

One study by the U.S. Food and Drug Administration showed that “the tobacco solution used in e-cigarettes contains a toxic chemical found in antifreeze and several cancer-causing chemicals,” according tocancer.net, the website of the American Society of Clinical Oncology.

In response to these concerns, some cities in Orange County have begun to impose restrictions on vaping.

The state Legislature is pushing to classify – and perhaps tax – vaping products as tobacco. And the U.S. Food and Drug Administration has drafted regulations that would require testing every strength of each flavor a manufacturer offers.

Under this rule, 80 variations of Freer’s products would need costly laboratory analysis that he says his small business can’t afford. Freer, along with many other vaping juice manufacturers, worries he might be forced out of the state – or out of business entirely – because of such regulations.

“If the FDA regs roll the way they’re proposed, I will find a new industry,” Freer said.
Austin Hopper, who has worked at three big e-liquid companies in Orange County, says proposed state legislation is too stringent. Lumping vaping liquids in with traditional tobacco products will only damage an industry that could help people quit smoking cigarettes, he warned.

“Being classified as tobacco is a stigma we don’t need,” Hopper said. “It is killing an industry that is saving people.”

Some researchers believe the opposite: that vaping may lead people to cigarettes.
“The FDA’s mandate is to protect Americans from tobacco-related disease and death in today’s rapidly evolving marketplace,” Michael Felberbaum, a press officer with the agency, wrote in response to an emailed question about its pending new e-cigarette regulations.

“Under the proposed rule, all newly deemed tobacco products would require market authorization” from the agency, Felberbaum noted. He added that the FDA is sympathetic to the concerns of small businesses and is proposing to stagger the compliance dates.

O.C.’s emerging “vapreneurs”

Many of the biggest names in the vaping industry are headquartered in Orange County, most of them led by young entrepreneurs.

“This is our Silicon Valley of vaping – of e-liquids certainly,” said Norm Bour, the founder of VapeMentors, a Newport Beach-based consultancy for what he calls “vapreneurs.”

Some e-liquid manufacturers point to the intersection of a hip emerging industry and the area’s status as a hub for drug and alcohol recovery services as the driving force behind vaping’s big foothold in Orange County.

Stores selling starter kits, e-liquid and the devices that turn it into vapor also have proliferated in Orange County with the popularity of vaping.

Data provided by Yelp show 238 Vape shops across Orange County opened and registered with the site over the past decade, most of them concentrated in the northern part of the county. Anaheim spawned the most, with 35 opening and listing on Yelp.

In 1963, the first patent for an e-cigarette was filed, but it would be four decades before a pharmacist in China developed a more sophisticated version of the e-cigarette. In the mid-2000s, e-cigarettes came to the U.S., and by 2009 their popularity had boomed.

By 2014, vaping had mushroomed into a $2.5 billion industry. This year the e-cigarette market is on track to grow to $3.5 billion, said Greg Conley, president of the New Jersey-based American Vaping Association. Most of the people benefiting from this exploding industry are the owners of small operations – shops employing a handful of workers.
“This is really a small business revolution,” Conley said.

‘Wild West’ of vaping

When e-cigarettes first caught on, there was no body of research measuring their health effects, and government officials were caught off guard by the need to classify, tax and regulate them. Business owners abounded, and the quality of the e-liquid they produced varied widely.

“It was a little bit of the Wild West when this industry started,” said Doug Hughes, a manufacturer and retailer of vaping products who is the co-president of the Southern California chapter of the Smoke-Free Alternatives Trade Association.

But the industry is no longer a free-for-all.

Several cities across Orange County are changing their laws to ban e-cigarette consumption in parks and public places. Under the regulations being prepared, the FDA is poised to crack down on free giveaways, require health warning labels, and generally treat e-cigarettes and vaping products much like traditional cigarettes.

Since the early days of vaping, academic studies monitoring its effects have appeared almost weekly. Some show more dire findings; others more benign.

One study released late last month by Public Health England, a UK government agency, found that most of the chemicals that cause smoking-related diseases are absent in vaping and that those that are in the vapor pose less of a risk.

Earlier this year, however, the California Department of Public Health determined that heated e-liquid delivers ultrafine particles that canbecome trapped in the lungs.

More ominously, a study by the New England Journal of Medicine published in January found the lifetime cancer risk from formaldehyde inhalation was significantly higher for long-term vapers than for cigarette smokers.

And yet another study published last month by JAMA Pediatrics found that young people who Vape are more likely to start smoking cigarettes.

“As an organization we are very concerned in having another generation addicted to nicotine,” said Cynthia Hallett, executive director of Americans for Nonsmokers’ Rights.
Vape business owners say they are concerned, too.

Freer launched the Vape Free Youth campaign and a set of standards for those in the industry to follow. The Smoke-Free Alternatives group is pushing Age to Vape, an effort asking businesses to hang signs in their stores showing their commitment to keep vaping products out of the hands of children.

“These products are for adults, sold by adults, and we want to keep these out of the hands of minors,” said Cynthia Cabrera, the executive director of the national Smoke-Free Alternatives Trade Association.

High-tech production

In preparation for stiff regulations, many manufacturers started about a year ago to move away from amateur methods and establish high-tech labs. Hughes estimated 10 percent of manufacturers don’t have high-quality labs.

Jeffrey Nelson left a job at a pharmaceutical company to join Cosmic Fog Vapors, a Costa Mesa-based maker of e-liquid, to prepare its facilities for a state-of-the-art lab. And he brought his expertise on FDA regulations with him.

“I realized this is not just a trend among a generation,” Nelson said of his decision. “This is a cultural shift.”

For Hopper, who has worked at three big-name e-liquid makers and recently launched his own line, Revol, in Orange County, some regulation is welcome.

“We need to be made in a lab,” Hopper said of the products. “We need regulations. We need a nomenclature that’s not geared toward children.”

Stuart Christensen of Laguna Beach said if regulations sent the cost of e-liquid skyrocketing he would stop buying it.

“I would probably try to start making my own,” he said.

Freer worries others will return to smoking cigarettes. And he said the extra regulations would push out the small businesses that have propelled the industry.

At that point, “the only kind of money that can do it is big tobacco and pharm,” Freer said. “This is small business, middle America latching onto brand new technology that really is a viable technology. We’re kind of the new electric car.”

Staff writer Jordan Graham contributed to this report.
Contact the writer: lwilliams@ocregister.com orjgraham@ocregister.com
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Thursday, September 17, 2015

Now selling - Liquid State Vapor eJuice








Liquid State Vapor launched their first product line of 4 select eJuices in August 2015.  Since then all four eJuices have been impressing not only myself but everyone else who has tried them.
 




​​Here is a brief run down on the 4 flavors and a short description:
1. Apple Butter - Washington, USA.  (CURRENT BEST SELLING EJUICE)
Sweet Washington apples slow cooked to caramelized perfection and blended with spiced cinnamon. The result? A taste that rivals your grandma's homemade apple pie.

2. Cali Colada - California, USA.
Taking a cue from the laid back California lifestyle, Cali Colada is a creamy, tropical pina colada with ripe juicy mango, sweet pineapple, and hints of guava. Sit back, relax, and enjoy the summer.

3. Cowboy Cobbler - Texas, USA
A traditional lone star dessert, fresh blueberry pomegranate cobbler with sweet cinnamon and buttery graham cracker crust. Not for your average cowboy.

4. Sweet Leaf - Georgia, USA
Life below the Mason Dixon line is just so sweet. Inspired by the peach state, sweet leaf embodies the flavors of the south. Our Georgia peach twist on sweet tea lemonade is a true southern charm.

Tuesday, August 11, 2015

ECC Aug. 13-16, 2015

NEXT EVENT: ECC 2015
August 13-16, 2015 at Fairplex in Pomona


ECC returns to SoCal in August for the ultimate B2B and consumer expo in the industry. 2 days of B2B and 2 days of the most exciting consumer expo experience in the world. Our 2015 Premier sponsor is Cosmic Fog Vapors, and our event will feature hundreds of the industry’s top brands such as Cosmic Fog Vapors, Space Jam Juice, Virgin Vapor, Baker White, Cuttwood, Buckshot Vapors, Glas, Flawless, Ruthless E-Juice, Local Vape, Blue Label Elixir, Vapor Shark, 3D Vapor, Innokin Technology, Giant Vapes, Vaping Monkey Distribution, Penguin E-Juice, Propaganda E-Liquid, 2puffs, Villain Vapors, BankCard USA, Apothecar•E Distribution, Boosted Premium E-Juice, Cartel Mods, Kangertech E-cigarettes, Banzai Vapors, and MANY more! Exhibitor Booth reservations can be made by joining the waiting list here or by messaging us on our Facebook Page. Follow us on Instagram @ecc_expo for additional announcements. Event registration for general attendance and B2B can be purchased here. ECC is and always has been an adult-only event. Must be 18 or older to enter.
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Costa Mesa. CA - Public vaping ban gets first approval

July 28, 2015
BY JORDAN GRAHAM / STAFF WRITER

COSTA MESA - The city has begun the process of banning vaping and electronic cigarette smoking in its public parks and city buildings in a move designed to protect residents from secondhand “smokeless” vapor.


The Planning Commission approved the ban Monday as part of a larger proposal that would lift a moratorium on hookah lounges and create rules for how and where new smoking lounges could operate. The ordinance will head to the City Council next Tuesday.

With the change, Costa Mesa would join 131 other California cities and counties that have passed laws to limit the use of e-cigarettes as of April, according to the Orange County Healthcare Agency. Anaheim, Garden Grove, Seal Beach, Mission Viejo, Laguna Hills and Laguna Niguel all have approved limitations.

Costa Mesa staff said the new ordinance was created simply to update the city’s existing smoking laws to include e-cigarettes, which vaporize liquid rather than burn tobacco. But other cities, such as San Clemente, have taken a “wait and see” approach to the devices, opting not to ban e-cigarettes, unsure whether secondhand vapor is as dangerous as secondhand smoke.

Amy Buch, of the OC Health Care Agency, said Monday that even though e-cigarettes don’t have combustible elements, they are still harmful. She pointed out that the California Department of Public Health declared e-cigarettes a health threat in January, when it released a report saying the devices emitted cancer-causing chemicals.

“(Cigarette bans) have been to protect nonsmokers,” Buch said. “Secondhand e-cigarette aerosol has been found to have at least 10 chemicals that are on California’s Proposition 65 list of chemicals known to cause cancer, birth defects or other reproductive harm... including nicotine, benzene, formaldehyde, nickel and lead...(though) not to the same extent that it would be in a traditional cigarette.”

Several vape shop owners and e-cigarette enthusiasts spoke at Monday’s meeting. While most praised the city’s ordinance for not placing burdensome restrictions on how vape shops can operate, they disputed the narrative that e-cigarettes are harmful.

“Vapor products are not a nuisance or a threat,” said Doug Hughes, co-president of the Southern California branch of the Smoke Free Alternative Trade Association. “Instead, they should be viewed as the most promising pathway to significantly reducing health care costs associated with smoking-related illnesses.”

Scientific studies have split on the danger of vaping, as well. Studies published in 2015 from the Public Library of Science ONE and Tobacco Control journals found e-cigarette smoke may harm the respiratory and immune systems. However, a July 12 study in the Toxicology in Vitro found e-vapor no more harmful than air.

California has had a similarly difficult time deciding how to treat the products. The state Legislature abandoned a bill July 8 that would have regulated e-cigarettes like other smoking tobacco, barring vaping in public places.

Costa Mesa’s proposed smoking lounge rules would allow hookah and vape lounges in some commercial shopping centers, such as The Triangle or Harbor Center, or in industrial properties. The ordinance would prohibit the lounges from opening within 1,500 feet of each other and within 500 feet of schools and parks.


Contact the writer: jgraham@ocregister.com or 714-796-7960, view the original article (HERE)
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